3) Biomedical Applicatons
We focus on improving bioperformance of nanomaterials, including photoacustic& photothermal effect, targeting ability, tumer penertration, expression level of ligand, etc.
In this part of work, I was mentored by Dr Yong Cheng, a former postdoctoral researcher in Jokerst Lab @UCSD.
Related projects are as following
prj 9. Protease-Responsive Peptide-Conjugated Mitochondrial-Targeting AIEgens for Selective Imaging and Inhibition of SARS-CoV-2-Infected Cells (Mentored by Dr Yong Cheng)
🌟 Cheng, Y., Clark, A.E., Zhou, J., He, T., Li, Y., Borum, R.M., Creyer, M.N., Xu, M., Jin, Z., Zhou, J. and Yim, W., 2022. Protease-Responsive Peptide-Conjugated Mitochondrial-Targeting AIEgens for Selective Imaging and Inhibition of SARS-CoV-2-Infected Cells. ACS nano, 16(8), pp.12305-12317.
prj 10. Peptide-doxorubicin complex for Sensing and Cleaving Mpro (Mentored by Dr Yong Cheng)
🌟 Co-author manuscript in preparation, aiming at Analitical Chemistry.