Design drug-mediated delivery of miRNA

Working on this multidisciplinary project gave me an insight into gene delivery and strengthened my problem-solving abilities for further research work. More importantly, I learned to apply my knowledge and previous experience to empirical analysis and real-world problems.

In my sophomore year, I started to focus on diseases besides cancer, like pulmonary hypertension (PAH). We set a team of five undergraduates from different majors and carried out a project for novel chemotherapy for PAH.
As the team leader, I contributed to addressing several critical issues, including applying for funding from companies, contacting faculty members for guidance, and designing technical routes. Besides, to make progress efficiently, I utilized what I learned in my last project on caveolae-mediated endocytosis and applied my knowledge in traditional Chinese medicine. Integrating this knowledge, we constructed a gene-drug co-delivery platform and confirmed its efficacy in animals.